<?xml version="1.0" encoding="utf-8"?><documents><rss version="2.0"><channel><title>Issues - Ibioinformatics</title><link>https://www.intbioinformaticsjr.com</link><description>Generated by Ibioinformatics.Source page: https://www.intbioinformaticsjr.com</description><language>en</language><mycatch><item><title>Contents</title><link>https://www.intbioinformaticsjr.com/Journal/lastissue/year/2017/month/June</link><description><p style="text-align: justify;">
	Contents</p>
</description><guid>https://www.intbioinformaticsjr.com/Journal/lastissue/year/2017/month/June</guid></item></mycatch><mycatch><item><title>Freshwater Micro-algal Diversity â€“Chlorococcales from Sawaimadhopur, Rajasthan, India</title><link>https://www.intbioinformaticsjr.com/Journal/lastissue/year/2017/month/June</link><description><p style="text-align: justify;">
	The fresh water bodies of Sawaimadhopur district, Rajasthan were surveyed for enlisting of different phytotoplankton diversity. The Chlrococcales are phototrophic micro-algal group with great diversity and cosmopolitan in their distribution. Forty two species were recorded and described in present paper from study area during January 2014 to Dec. 2015. The fluctuation and blooming of Chlrococcales are important criteria to describe healthy condition of water bodies. The present work is first systematic report of Chlorococcales from this tourist and historical important area.</p>
</description><guid>https://www.intbioinformaticsjr.com/Journal/lastissue/year/2017/month/June</guid></item></mycatch><mycatch><item><title>Integrative Analysis of CXCR4/CXCL12 Axis Gene Expression Alterations in Breast Cancer and its Prognostic Relevance</title><link>https://www.intbioinformaticsjr.com/Journal/lastissue/year/2017/month/June</link><description><p style="text-align: justify;">
	Cancer metastasis is the major delimiting factor in the failure of therapeutic strategies currently practised and epithelial-mesenchymal transition (EMT) has been observed to be one of the key regulators of metastasis as it confers the invasive phenotype. Chemokines have been shown to be directly involved in mediating the metastatic ability of cancer cells, particularly CXCR4 chemokine receptor. The purpose of the present study was to explore the expression levels of CXCR4/CXCL12 axis in different subtypes of breast cancer using dataset analysis. The mRNA expression levels and genomic alterations of CXCR4 and CXCL12 in different cancers were analyzed via the Oncomine and Cbioportal. In addition, co-expression analysis and clinical survival relevance has been analysed in various datasets. Results of our analysis suggest a significant association of CXCR4/CXCL12 axis in breast cancer as a prognostic biomarker.</p>
</description><guid>https://www.intbioinformaticsjr.com/Journal/lastissue/year/2017/month/June</guid></item></mycatch><mycatch><item><title>Isolation and identification of Novel Lipase-producing Bacterium Aneurinibacillus aneurinilyticus LP-II</title><link>https://www.intbioinformaticsjr.com/Journal/lastissue/year/2017/month/June</link><description><p style="text-align: justify;">
	The aim of this research work was to isolate novel strain of lipase producer from local oil mill soil at Gangakhed. The lipase can be catalysing the transesterification of algae oil in to biodiesel. A sample of soil was collected from oil mill and enrichment the soil sample with basal lipase production media containing 1% Algae oil as a carbon source. Lipase producing microbes were screened on tributyrin agar plates, the activity of crude enzyme were determined. The isolate produced lipase and showed maximum activity 1.5 U/mL at 40anddeg;C and at 7.0 PH, after 48 hours of incubation period at 150 rpm. Isolate identified by morphological, biochemical and 16s r-RNA sequencing gene. The 16s r-RNA sequencing revealed it is a new strain of Aneurinibacillus aneurinilyticus LP-II.</p>
</description><guid>https://www.intbioinformaticsjr.com/Journal/lastissue/year/2017/month/June</guid></item></mycatch><mycatch><item><title>MicroRNAs In Pathogenesis of Diabetic Retinopathy</title><link>https://www.intbioinformaticsjr.com/Journal/lastissue/year/2017/month/June</link><description><div style="text-align: justify;">
	A novel non-transmissible pandemic obesity has escalated the incidence rate of diabetes in present world population. Both T1D and T2D are associated with considerably accelerated rates of multiple microvascular as well as macrovascular complications. Diabetic retinopathy is one of the most debilitating chronic impediments, although the exact mechanism(s) responsible for how retina is damaged in diabetes remains unclear. Although the key risk factors contributing to these complications like hyperglycemia, hyperlipidemia, advanced glycation end products, growth factors and inflammatory molecules are well-identified, the currently available therapies are not completely efficacious. Therefore there is an imperative requirement for a better elucidation of the molecular machinery underlying the high incidence of diabetic complications in order to identify newer therapeutic and prognostic markers. MicroRNAs are short non-coding RNAs that can repress target gene expression via post-transcriptional mechanisms and involved in a number of biological processes, including the pathogenesis of diseases. Easily detectable and consistent alterations in microRNA levels in body fluids of the patients due to hyperglycemia-induced epigenetic alterations of metabolic events make them an attractive candidate for early diagnosis prior to clinical manifestation of disease. Also, a number of such microRNAs exhibit therapeutic potential enhancing the provision for improved management of diabetes and associated complications like DR. Herein, the role of microRNAs in the pathobiology of diabetic retinopathy has been elaborated considering their possible utilization as biomarkers and therapeutic targets.</div>
</description><guid>https://www.intbioinformaticsjr.com/Journal/lastissue/year/2017/month/June</guid></item></mycatch><mycatch><item><title>Knowledge and Perception on the Interrelationship between Biodiversity and Human Health in Lagos, Nigeria</title><link>https://www.intbioinformaticsjr.com/Journal/lastissue/year/2017/month/June</link><description><p style="text-align: justify;">
	As modern society emerged, and the human population condensed into urban areas, industrialization disallowed many people from reliance on direct consumptive interactions with nature. Although, there is mounting empirical evidence that interacting with nature delivers measurable benefits to people. However, contributions from ecologists are few in number, perhaps hindering the identification of key ecological features of the natural environment that deliver human benefits. This study therefore assessed peoplesandrsquo; knowledge and perception on the interrelationship between biodiversity and human health. A mixed method of data collection was used and these include combining data from surveys, document reviews, information from participants and key informants through questionnaire (301) and oral interviews. Result revealed that larger percentage of the respondents were male (71.9%) while 28.1% were female. 51.7% of the respondents strongly agreed and understood the impacts of biodiversity on mental health. This is followed by those that agree (41.3%) to a lower degree. 4.7% of the respondents were not sure. Majority of the people (70.4%) strongly opined that mental health describes the balanced and emotional state of mind; and that it is irrespective of age and social status (71.3% and 22.3%). They further strongly agreed that nature and living things in the environment makes human feels good (70.1%)., a greater part of the respondents strongly agree that exposure to nature have restorative effects (66.4%) and 29.5% agreed with this. 45.1% and 49.2% strongly agreed and agreed respectively that participation in outdoor recreation can lead to mental health improvement. Biodiversity is important and should be conserved for its values and benefits to human health and well-being. Increased understanding of these health benefits may improve public support for conservation.</p>
</description><guid>https://www.intbioinformaticsjr.com/Journal/lastissue/year/2017/month/June</guid></item></mycatch><mycatch><item><title>FTIR Spectroscopic Analysis on Marine Molluscan Shells</title><link>https://www.intbioinformaticsjr.com/Journal/lastissue/year/2017/month/June</link><description><p style="text-align: justify;">
	The paper presents IR data on 4 species of marine molluscan shells collected from Vizag seashore. It is observed that irrespective of species, the mineralogical from of CaCO3 is aragonite. This is due to the fact that Mg present in the shell material acts as a regulator for the deposition of CaCO3. The paper suggests that infrared spectroscopy may be useful to provide valuable information in the biological system as it affords rapid qualitative and identification of biominerals.</p>
</description><guid>https://www.intbioinformaticsjr.com/Journal/lastissue/year/2017/month/June</guid></item></mycatch><mycatch><item><title>Bio Informatics in Private Universities in India: An Emerging Study on Promotion of Biological Information Sciences</title><link>https://www.intbioinformaticsjr.com/Journal/lastissue/year/2017/month/June</link><description><p style="text-align: justify;">
	Information Science is an interdisciplinary domain and plays a great role in the development at large. Information Science and Informatics normally treated as a synonym in academia worldwide. Information Science/Informatics is an applied science branch and thus with the combination of other areas and subject created many other knowledge cluster and field viz. Geo Information Science, Chemo Information Sciences, Environmental Information Science. Bio Information Sciences may be considered as a field of intersection of Biology and Information Science. Bio Informatics may be treated as one of the areas of Bio Information Sciences. Indian universities moving towards education, training, and research in interdisciplinary fields and as a result Bio related Informatics become vital. Higher Educational Institutionandrsquo;s number wise India also holds a rank in the world. In recent past private universities expanded rapidly. Many of them started offering Bio Informatics program in different level of study. This is a theoretical framework in terms of research paper and here several knowledge on information sciences, informatics with reference to Bio Informatics have been provided. The paper also highlighted emerging other allied areas including future potentialities in brief.</p>
</description><guid>https://www.intbioinformaticsjr.com/Journal/lastissue/year/2017/month/June</guid></item></mycatch></channel></rss></documents>